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题目:: [Enhancement of mononuclear leukocyte-mediated anti-tumoral activity by cells of the B cell-line].
作者:: Takamura(S)
状态:: 发布时间1990-05-07 , 更新时间 2008-11-21
期刊:: Gan No Rinsho
摘要:: Cytotoxic activity of human mononuclear leukocytes (MNLs) against various tumor cell-line cells was induced by irradiated B cell-line cells. Each B cell-line cell was found to have a different potentiality and time kinetics on the induction of cytotoxicity. The enhancing effect of some B cell-line cells was found to be related to the IL-2 production from the MNLs, but not related to the IFN, TNF, and LT production. An analysis of the effector cells of the B cell-activating-killer cells (BAK) indicated that the population of the major effector cells were monocytes and NK cells. These results have provided evidence that B cell-line cells are capable of enhancing nonspecific cytotoxic activity of the MNLs, and that they might be new biological response modifiers of cancer immunotherapy.
语言:: jpn
DOI:

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