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PMID: 21071412 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't

The IMGT/HLA database.

Nucleic acids research ·Vol. 39 ·No. Database issue ·2011-01-00 ·Pages D1171-6

Robinson J, Mistry K, McWilliam H, Lopez R, Parham P, Marsh SG

Abstract

It is 12 years since the IMGT/HLA database was first released, providing the HLA community with a searchable repository of highly curated HLA sequences. The HLA complex is located within the 6p21.3 region of human chromosome 6 and contains more than 220 genes of diverse function. Many of the genes encode proteins of the immune system and are highly polymorphic. The naming of these HLA genes and alleles and their quality control is the responsibility of the WHO Nomenclature Committee for Factors of the HLA System. Through the work of the HLA Informatics Group and in collaboration with the European Bioinformatics Institute, we are able to provide public access to this data through the web site http://www.ebi.ac.uk/imgt/hla/. Regular updates to the web site ensure that new and confirmatory sequences are dispersed to the HLA community, and the wider research and clinical communities.

MeSH Terms
Alleles Databases, Protein HLA Antigens/chemistry,genetics Humans Software Terminology as Topic
Chemicals
HLA Antigens
Authors & Affiliations
6 authors, click to expand affiliations / ORCID
Robinson James
Anthony Nolan Research Institute, Royal Free Hospital, Pond Street, Hampstead, London NW3 2QG, UK.
Mistry Kavita
McWilliam Hamish
Lopez Rodrigo
Parham Peter
Marsh Steven G E
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Article Info
Journal
Nucleic acids research
Abbr.
Nucleic Acids Res
ISSN
1362-4962
DOI
10.1093/nar/gkq998
Published
2011-01-00
Epub
2010-00-11
Pages
D1171-6
Language
English
Region
England
NLM ID
0411011
PMCID
PMC3013815
Subset
IM
Grants
Cancer Research UK · United Kingdom
External Links
PubMed source DOI: 10.1093/nar/gkq998 PMC Full Text View journal details
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