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PMID: 20836670 Published · ppublish English Clinical Conference Journal Article

American Society of Clinical Oncology 2010: report of selected studies from the CNS tumors section.

Expert review of anticancer therapy ·Vol. 10 ·No. 9 ·2010-09-00 ·Pages 1367-9

Wen PY

Abstract

A number of important studies were presented at the CNS tumors section of the 2010 American Society of Oncology (ASCO) Annual Meeting. There was particular interest in a Phase II study showing that the mTOR inhibitor everolimus had significant activity in tuberous patients with subependymal giant cell astrocytomas. Two Phase III studies reported on the relative benefits of radiotherapy and chemotherapy in elderly patients with glioblastomas. Other studies focused on promising new agents such as XL184 and ANG1005.

MeSH Terms
Aged Astrocytoma/drug therapy Central Nervous System Neoplasms/drug therapy Clinical Trials as Topic Everolimus Glioblastoma/drug therapy,radiotherapy Humans Immunosuppressive Agents/therapeutic use Sirolimus/analogs & derivatives,therapeutic use Tuberous Sclerosis/drug therapy
Chemicals
Immunosuppressive Agents Everolimus Sirolimus
Authors & Affiliations
1 authors, click to expand affiliations / ORCID
Wen Patrick Y
Division of Cancer Neurology, Department of Neurology, Brigham and Women's Hospital, 75 Francis Street, Boston, MA 02115, USA. pywen@partners.org
Article Info
Journal
Expert review of anticancer therapy
Abbr.
Expert Rev Anticancer Ther
ISSN
1744-8328
Published
2010-09-00
Pages
1367-9
Language
English
Region
England
NLM ID
101123358
Subset
IM
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