Differential DNA damage response in stem and progenitor cells.
作者:
Seita(Jun),Rossi(Derrick J),Weissman(Irving L)
状态:
发布时间2010-08-04
, 更新时间 2016-05-18
期刊:
Cell Stem Cell
摘要:
The long lifespan of tissue-specific stem cells suggests that they may respond differently to DNA damage than downstream cells. In this issue of Cell Stem Cell, two groups address this hypothesis by examining DNA damage responses in hematopoietic stem and progenitor cells (Milyavsky et al., 2010; Mohrin et al., 2010).