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PMID: 2063193 Published · ppublish English Journal Article Research Support, U.S. Gov't, P.H.S. Review

Blood pressure control--special role of the kidneys and body fluids.

Science (New York, N.Y.) ·Vol. 252 ·No. 5014 ·1991-06-28 ·Pages 1813-6

Guyton AC

Abstract

The arterial pressure of the adult human rarely deviates from normal by more than 10 to 15 percent during each day. To achieve such constancy, the body has a network of pressure control systems. Several are based on neural receptors that respond within seconds to help correct any abnormal pressure. The activities of these systems are followed within minutes by activation of hormonal controllers. Within hours or days, a kidney pressure control system is induced that increases body fluid volume when the pressure falls (or decreases the volume when the pressure rises). This kidney-fluid system is the dominant method of establishing long-term pressure control.

MeSH Terms
Adult Animals Blood Pressure/physiology Body Fluids/physiology Chemoreceptor Cells/physiology Homeostasis Humans Kidney/physiology Nervous System Physiological Phenomena Pressoreceptors/physiology
Authors & Affiliations
1 authors, click to expand affiliations / ORCID
Guyton A C
Department of Physiology and Biophysics, University of Mississippi School of Medicine, Jackson 39216.
Article Info
Journal
Science (New York, N.Y.)
Abbr.
Science
ISSN
0036-8075
Published
1991-06-28
Pages
1813-6
Language
English
Region
United States
NLM ID
0404511
Subset
IM
Grants
NHLBI NIH HHS · HL 11678-23 · United States
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