The influence of dibutyryl cGMP on the rabbit auricle.

Polish journal of pharmacology and pharmacy ·Vol. 30 ·No. 1 ·1978-00-00 ·Pages 73-5

Tuganowski W, Kopeć P, Gorczyca J, Tarnowski W, Grudzień E

Abstract

Dibutyryl cGMP, like acetylcholine, shortens and reduces repolarization and overshoot of the action potential, slightly hyperpolarizes the cell and decreases the force of the contraction in the atrial working muscle. It suggests that cGMP may mediate the action of acetylcholine in the atrial working fibres.

MeSH Terms

Acetylcholine/pharmacology Animals Cyclic GMP/analogs & derivatives Depression, Chemical Dibutyryl Cyclic GMP/pharmacology Heart Atria/drug effects Myocardial Contraction/drug effects Rabbits

Chemicals

Dibutyryl Cyclic GMP Cyclic GMP Acetylcholine

Authors & Affiliations

5 authors, click to expand affiliations / ORCID

Tuganowski W

Kopeć P

Gorczyca J

Tarnowski W

Grudzień E

Article Info

Journal

Polish journal of pharmacology and pharmacy

Abbr.

Pol J Pharmacol Pharm

ISSN

0301-0244

Published

1978-00-00

Pages

73-5

Language

English

Region

Poland

NLM ID

0366561

Subset

External Links

PubMed source

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The influence of dibutyryl cGMP on the rabbit auricle.

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