Home LiteratureArticle Details
PMID: 20482022 Published · ppublish English Journal Article Research Support, N.I.H., Extramural Research Support, U.S. Gov't, Non-P.H.S.

Transient localized patterns in noise-driven reaction-diffusion systems.

Physical review letters ·Vol. 104 ·No. 15 ·2010-04-16 ·Pages 158301

Hecht I, Kessler DA, Levine H

Abstract

Noise can induce excitable systems to make time-limited transitions between quiescent and active states. Here we investigate the possibility that these transitions occur locally in a spatially extended medium, leading to the occurrence of spatiotemporal patches of activation. We show that this can in fact occur in a parameter range such that there exist (in general unstable) localized solutions of the governing deterministic reaction-diffusion equations. Our work is motivated by a recent biological example showing transiently excited cell membrane regions.

MeSH Terms
Cyclic AMP/pharmacology Dictyostelium/cytology,drug effects,metabolism Diffusion Kinetics Models, Theoretical Time Factors
Chemicals
Cyclic AMP
Authors & Affiliations
3 authors, click to expand affiliations / ORCID
Hecht Inbal
Center for Theoretical Biological Physics, University of California San Diego, La Jolla, California 92093-0319, USA.
Kessler David A
Levine Herbert
References (15)
15 references, click to expand
  1. Localized structures in dryland vegetation: forms and functions.
    Chaos. 2007 Sep;17(3):037109 PMID: 17903016
  2. Localized Ras signaling at the leading edge regulates PI3K, cell polarity, and directional cell movement.
    J Cell Biol. 2004 Nov 8;167(3):505-18 PMID: 15534002
  3. Scenarios of domain pattern formation in a reaction-diffusion system.
    Phys Rev E Stat Phys Plasmas Fluids Relat Interdiscip Topics. 1996 Nov;54(5):4860-4879 PMID: 9965667
  4. Membrane-bound Turing patterns.
    Phys Rev E Stat Nonlin Soft Matter Phys. 2005 Dec;72(6 Pt 1):061912 PMID: 16485979
  5. Excitability mediated by localized structures in a dissipative nonlinear optical cavity.
    Phys Rev Lett. 2005 Feb 18;94(6):063905 PMID: 15783734
  6. Uniform cAMP stimulation of Dictyostelium cells induces localized patches of signal transduction and pseudopodia.
    Mol Biol Cell. 2003 Dec;14(12):5019-27 PMID: 14595105
  7. Receptor noise and directional sensing in eukaryotic chemotaxis.
    Phys Rev Lett. 2008 Jun 6;100(22):228101 PMID: 18643461
  8. Wave nucleation rate in excitable systems in the low noise limit.
    Phys Rev E Stat Nonlin Soft Matter Phys. 2003 Sep;68(3 Pt 1):031914 PMID: 14524810
  9. Orientation of chemotactic cells and growth cones: models and mechanisms.
    J Cell Sci. 1999 Sep;112 ( Pt 17):2867-74 PMID: 10444381
  10. Temporally harmonic oscillons in newtonian fluids
    Phys Rev Lett. 2000 Jul 24;85(4):756-9 PMID: 10991391
  11. Self-organization in an excitable reaction-diffusion system. III. Motionless localized versus propagating-pulse solutions.
    Phys Rev A. 1992 Jun 15;45(12):8374-8382 PMID: 9906936
  12. Models of eukaryotic gradient sensing: application to chemotaxis of amoebae and neutrophils.
    Biophys J. 2002 Jan;82(1 Pt 1):50-63 PMID: 11751295
  13. An excitable gene regulatory circuit induces transient cellular differentiation.
    Nature. 2006 Mar 23;440(7083):545-50 PMID: 16554821
  14. Localized patterns in reaction-diffusion systems.
    Chaos. 2007 Sep;17(3):037110 PMID: 17903017
  15. A cell's sense of direction.
    Science. 1999 Apr 30;284(5415):765-70 PMID: 10221901
Article Info
Journal
Physical review letters
Abbr.
Phys Rev Lett
ISSN
1079-7114
Published
2010-04-16
Epub
2010-00-14
Pages
158301
Language
English
Region
United States
NLM ID
0401141
PMCID
PMC2882887
Subset
IM
Grants
NIGMS NIH HHS · P01 GM078586 · United States
NIGMS NIH HHS · P01 GM078586-03 · United States
Analysis Services
Analysis Services

Contact

No. 2 Wenbo Road, Zhangqiu District, Jinan, Shandong

Qilu Normal University · Genelibs Bioinformatics Lab

750 Shunhua Rd, Jinan

2F, Bldg F, University Science Park

Tel: 0531-88819269

WeChat Official Account

Follow our WeChat subscription account for real-time updates and the latest in medical and biological research.


Business Email

E-mail: product@genelibs.com