Integrin alpha 6: anchors away for glioma stem cells.
作者:
Corsini(Nina S),Martin-Villalba(Ana)
状态:
发布时间2010-05-10
, 更新时间 2016-05-18
期刊:
Cell Stem Cell
摘要:
The laminin receptor Integrin alpha6beta1 anchors adult neural stem cells to the niche vasculature. In this issue of Cell Stem Cell, Lathia et al. (2010) show that glioblastoma stem cells highly express integrin alpha6 and that their interaction with laminin on endothelial cells directly regulates their tumorigenic capacity.