| GeneLibs

题目:: ES and iPS cell research for cardiovascular regeneration.
作者:: Yamashita(Jun K)
状态:: 发布时间2010-08-20 , 更新时间 2010-08-20
期刊:: Exp Cell Res
摘要:: Embryonic stem (ES) cells and induced pluripotent stem (iPS) cells, which are ES-like stem cells induced from adult tissues, are twin stem cells with currently (with the exception of fertilized eggs) the broadest differentiation potentials. These two stem cells show various similarities in appearance, maintenance methods, growth and differentiation potentials, i.e. theoretically, those cells can give rise to all kinds of cells including germ-line cells. Generation of human ES and iPS cells is further facilitating the researches towards the realization of regenerative medicine. The following three issues are important purposes of ES and iPS cell researches for regenerative medicine: (1) dissection of differentiation mechanisms, (2) application to cell transplantation, and (3) drug discovery. In this review, the current status of cardiovascular regenerative trials using ES and iPS cells is briefly discussed.
语言:: eng
DOI:: 10.1016/j.yexcr.2010.04.004

文献库文献相关信息