The hair follicle bulge stem cell niche resists transformation by the hedgehog pathway.
作者:
Ridky(Todd W),Khavari(Paul A)
状态:
发布时间2010-04-05
, 更新时间 2016-11-22
期刊:
Cell Stem Cell
摘要:
Similarities between basal cell carcinoma (BCC) tumor cells and hair follicle keratinocytes had previously suggested that BCC originates within the hair follicle bulge stem cell niche. However, in the current Nature Cell Biology, Youssef et al. (2010) show that BCC instead originates in the interfollicular epidermis.