Finding the right dose for cancer therapeutics--can we do better?
作者:
Rubin(Eric H),Anderson(Keaven M)
状态:
发布时间2010-02-16
, 更新时间 2010-02-16
期刊:
Clin Cancer Res
摘要:
Unlike other diseases, dose-selection for cancer therapeutics is often based on the maximum-tolerated dose in phase 1 studies involving relatively few patients. In this issue of Clinical Cancer Research, Jain and colleagues provide evidence that lower doses may be as effective as maximum-tolerated doses in the treatment of cancer patients.