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题目:: PI3K regulatory subunits lose control in cancer.
作者:: Berenjeno(Inma Martin),Martin-Berenjeno(Inma),Vanhaesebroeck(Bart)
状态:: 发布时间2009-12-07 , 更新时间 2016-12-03
期刊:: Cancer Cell
摘要:: The PI3K signaling axis is frequently activated in cancer resulting from inactivation of its negative regulator PTEN or activating mutations of the p110alpha catalytic subunit of PI3K. In this issue of Cancer Cell, Jaiswal et al. report that mutations in the p85alpha regulatory subunit of PI3K can also activate this pathway in cancer.
语言:: eng
DOI:: 10.1016/j.ccr.2009.11.017

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