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PMID: 1995059 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't

Low potassium-type but not high potassium-type sheep red blood cells show passive K+ transport induced by low ionic strength.

Biochimica et biophysica acta ·Vol. 1061 ·No. 1 ·1991-01-09 ·Pages 85-8

Erdmann A, Bernhardt I, Pittman SJ, Ellory JC

Abstract

Low potassium-type (LK) sheep red blood cells show a significant increase of the residual (i.e., ouabain-insensitive) K+ influx when the ionic strength of the solution is decreased. This effect is absent from high potassium-type (HK) sheep red blood cells. The KCl cotransport system is not involved since three different manoeuvres to suppress the KCl cotransport (replacement of Cl- by NO3-, volume-decrease, inhibition by anti-L1 antibodies) have no effect on the low ionic strength-stimulated K+ influx.

MeSH Terms
Animals Biological Transport Carrier Proteins/blood Chlorides/blood Erythrocyte Volume Erythrocytes/metabolism Osmolar Concentration Ouabain/pharmacology Potassium/blood Sheep Symporters
Chemicals
Carrier Proteins Chlorides Symporters potassium-chloride symporters Ouabain Potassium
Authors & Affiliations
4 authors, click to expand affiliations / ORCID
Erdmann A
Department of Biophysics, Humboldt University, Berlin, G.D.R.
Bernhardt I
Pittman S J
Ellory J C
Article Info
Journal
Biochimica et biophysica acta
Abbr.
Biochim Biophys Acta
ISSN
0006-3002
Published
1991-01-09
Pages
85-8
Language
English
Region
Netherlands
NLM ID
0217513
Subset
IM
Grants
Wellcome Trust · United Kingdom
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