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PMID: 199355 Published · ppublish English Journal Article Research Support, U.S. Gov't, Non-P.H.S. Research Support, U.S. Gov't, P.H.S.

Further characterization of Sendai virus DI-RNAs: a model for their generation.

Cell ·Vol. 12 ·No. 2 ·1977-10-00 ·Pages 539-52

Leppert M, Kort L, Kolakofsky D

Abstract

Sendai virus DI-RNAs which contain complementary ends have been characterized as follows. First, the complementary ends of three DI-RNAs, although somewhat different in size (110-150 base pairs), contain sequences that are both identical to each other and to the 5' end of the nondefective (ND) genome. Second, almost all the sequences contained sequences that are both identical to each other and to the 5' end of the nondefective (ND) genome. Second, almost all the sequences contained in the DI-RNAs derive from sequences that are contiguous to the 5' end of the ND genome. The ND genome, on the other hand, does not contain any sequences that are complementary to its 5' end. A genetic map and a model for the generation of the Sendai DI-RNAs are presented.

MeSH Terms
Base Sequence Defective Viruses/genetics,metabolism Genes, Viral Models, Biological Nucleic Acid Conformation Parainfluenza Virus 1, Human/genetics,metabolism RNA, Viral/analysis,biosynthesis,genetics
Chemicals
RNA, Viral
Authors & Affiliations
3 authors, click to expand affiliations / ORCID
Leppert M
Kort L
Kolakofsky D
Article Info
Journal
Cell
Abbr.
Cell
ISSN
0092-8674
Published
1977-10-00
Pages
539-52
Language
English
Region
United States
NLM ID
0413066
Subset
IM
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