Home LiteratureArticle Details
PMID: 19922862 Published · ppublish English Comment Journal Article

Sorting out endosomes in the WASH.

Developmental cell ·Vol. 17 ·No. 5 ·2009-11-00 ·Pages 583-4

Bear JE

Abstract

Two new studies published in this issue of Developmental Cell by Derivery et al. and Gomez and Billadeau reveal that WASH (Wiskott-Aldrich syndrome protein and SCAR homolog) activates Arp2/3 on endosomes and plays a critical role in the fission of tubules that serve as transport intermediates during endosome sorting.

MeSH Terms
Actin-Related Protein 2-3 Complex/metabolism Animals Endosomes/metabolism Humans Protein Transport Wiskott-Aldrich Syndrome Protein/metabolism
Chemicals
Actin-Related Protein 2-3 Complex Wiskott-Aldrich Syndrome Protein
Authors & Affiliations
1 authors, click to expand affiliations / ORCID
Bear James E
HHMI, Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC 27514, USA. jbear@email.unc.edu
Article Info
Journal
Developmental cell
Abbr.
Dev Cell
ISSN
1878-1551
DOI
10.1016/j.devcel.2009.10.019
Email
jbear@email.unc.edu
Published
2009-11-00
Pages
583-4
Language
English
Region
United States
NLM ID
101120028
Subset
IM
Corrections
ErratumIn
-
CommentOn
PMID: 19922874
CommentOn
PMID: 19922875
External Links
PubMed source DOI: 10.1016/j.devcel.2009.10.019 View journal details
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