Preview. Inhibition of Tgf-beta signaling improves mouse fibroblast reprogramming.
作者:
Woltjen(Knut),Stanford(William L)
状态:
发布时间2009-11-09
, 更新时间 2016-05-18
期刊:
Cell Stem Cell
摘要:
Circumventing genomic modification in induced pluripotent stem cell (iPSC) derivation is a clear requirement to realize safe clinical applications. In this issue of Cell Stem Cell, Ichida et al., (2009) describe a small molecule capable of replacing Sox2, offering insight into the reprogramming process.