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题目:: Hepato-biliary late effects in survivors of childhood and adolescent cancer: a report from the Children's Oncology Group.
作者:: Castellino(Sharon),Muir(Andrew),Shah(Ami),Shope(Sheila),McMullen(Kevin),Ruble(Kathy),Barber(Ashley),Davidoff(Andrew),Hudson(Melissa M)
状态:: 发布时间2010-03-15 , 更新时间 2016-10-19
期刊:: Pediatr Blood Cancer
摘要:: Curative therapy for childhood and adolescent cancer translates to 1 in 640 young adults being a survivor of cancer. Although acute hepato-biliary toxicity occurs commonly during pediatric cancer therapy, the impact of antineoplastic therapy on long-term liver health in childhood/adolescent cancer survivors is unknown. This article reviews the medical literature on late liver dysfunction following treatment for childhood/adolescent cancer. We also outline the Children's Oncology Group (COG) guidelines for screening and follow-up of hepato-biliary sequelae. As the population of survivors grow and age, vigilance for risks to hepatic health needs to continue based on specific exposures during curative cancer therapy.
语言:: eng
DOI:

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