STUDIES CONCERNING THE SITE OF RENIN FORMATION IN THE KIDNEY : IV. THE RENIN CONTENT OF THE MAMMALIAN KIDNEY FOLLOWING SPECIFIC NECROSIS OF PROXIMAL CONVOLUTED TUBULAR EPITHELIUM.
1. The administration of tartrate to adult rabbits was found to produce in some of them, a profound and widespread necrosis of the proximal convoluted tubular epithelium without affecting the other portions of the nephrons. 2. The markedly damaged kidneys were found to be almost completely devoid of pressor substance (renin), indicating that in the mammalian kidney, the epithelium of the proximal convoluted tubules is concerned in the formation or storage of renin.
4 references, click to expand
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TARTRATE NEPHRITIS, WITH ESPECIAL REFERENCE TO SOME OF THE CONDITIONS UNDER WHICH IT MAY BE PRODUCED.J Exp Med. 1913 Oct 1;18(4):322-46 PMID: 19867709
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A STUDY OF RENAL SECRETION DURING TARTRATE NEPHRITIS.J Exp Med. 1913 Oct 1;18(4):347-52 PMID: 19867710
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STUDIES CONCERNING THE SITE OF RENIN FORMATION IN THE KIDNEY : I. THE ABSENCE OF RENIN IN THE AGLOMERULAR KIDNEY OF THE MIDSHIPMAN FISH.J Exp Med. 1942 Jan 1;75(1):127-34 PMID: 19871164
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STUDIES CONCERNING THE SITE OF RENIN FORMATION IN THE KIDNEY : III. THE APPARENT SITE OF RENIN FORMATION IN THE TUBULES OF THE MESONEPHROS AND METANEPHROS OF THE HOG FETUS.J Exp Med. 1942 Sep 1;76(3):307-16 PMID: 19871238
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