QUANTITATIVE CHEMICAL STUDIES ON COMPLEMENT OR ALEXIN : III. UPTAKE OF COMPLEMENT NITROGEN UNDER VARYING EXPERIMENTAL CONDITIONS.

The Journal of experimental medicine ·Vol. 74 ·No. 4 ·1941-09-30 ·Pages 359-67

Heidelberger M, Rocha E Silva M, Mayer M

Abstract

1. Quantitative data are given on the effect of variations in the time of contact and the proportions of the reactants on the quantity of complement combining component nitrogen (C'1 N) found in active guinea pig serum. 2. C'1 N was the same when determined with precipitates containing excess antibody or excess antigen. 3. Finely divided specific precipitates took up the complement combining component (C'1) from subsequently added guinea pig serum almost as well as specific precipitates formed in the presence of complement.

Authors & Affiliations

3 authors, click to expand affiliations / ORCID

Heidelberger M

Departments of Medicine and Biochemistry, College of Physicians and Surgeons, Columbia University, and the Presbyterian Hospital, New York.

Rocha E Silva M

Mayer M

References (7)

7 references, click to expand

THE COMPLEMENT FIXATION REACTION WITH PNEUMOCOCCUS CAPSULAR POLYSACCHARIDE.
J Exp Med. 1936 Jul 31;64(2):201-16 PMID: 19870530
CHEMICAL STUDIES ON BACTERIAL AGGLUTINATION : III. A REACTION MECHANISM AND A QUANTITATIVE THEORY.
J Exp Med. 1937 May 31;65(6):885-902 PMID: 19870642
QUANTITATIVE STUDIES ON THE PRECIPITIN REACTION : ANTIBODY PRODUCTION IN RABBITS INJECTED WITH AN AZO PROTEIN.
J Exp Med. 1933 Jul 31;58(2):137-52 PMID: 19870185
THE PRECIPITIN REACTION BETWEEN TYPE III PNEUMOCOCCUS POLYSACCHARIDE AND HOMOLOGOUS ANTIBODY : III. A QUANTITATIVE STUDY AND A THEORY OF THE REACTION MECHANISM.
J Exp Med. 1935 Mar 31;61(4):563-91 PMID: 19870380
QUANTITATIVE CHEMICAL STUDIES ON COMPLEMENT OR ALEXIN : II. THE INTERRELATION OF COMPLEMENT WITH ANTIGEN-ANTIBODY COMPOUNDS AND WITH SENSITIZED RED CELLS.
J Exp Med. 1941 May 31;73(6):695-709 PMID: 19871106
QUANTITATIVE CHEMICAL STUDIES ON COMPLEMENT OR ALEXIN : I. A METHOD.
J Exp Med. 1941 May 31;73(6):681-94 PMID: 19871105
A QUANTITATIVE THEORY OF THE PRECIPITIN REACTION : III. THE REACTION BETWEEN CRYSTALLINE EGG ALBUMIN AND ITS HOMOLOGOUS ANTIBODY.
J Exp Med. 1935 Oct 31;62(5):697-720 PMID: 19870443

Article Info

Journal

The Journal of experimental medicine

Abbr.

J Exp Med

ISSN

0022-1007

DOI

10.1084/jem.74.4.359

Published

1941-09-30

Pages

359-67

Language

English

Region

United States

NLM ID

2985109R

PMCID

PMC2135192

External Links

PubMed source DOI: 10.1084/jem.74.4.359 PMC Full Text View journal details

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QUANTITATIVE CHEMICAL STUDIES ON COMPLEMENT OR ALEXIN : III. UPTAKE OF COMPLEMENT NITROGEN UNDER VARYING EXPERIMENTAL CONDITIONS.

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