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PMID: 19871087 Published · ppublish English Journal Article

STUDIES ON THE SENSITIZATION OF ANIMALS WITH SIMPLE CHEMICAL COMPOUNDS : IX. SKIN SENSITIZATION INDUCED BY INJECTION OF CONJUGATES.

The Journal of experimental medicine ·Vol. 73 ·No. 3 ·1941-02-28 ·Pages 431-8

Landsteiner K, Chase MW

Abstract

Experiments with guinea pigs are described which show that under special experimental conditions the intraperitoneal injection of conjugates made with homologous erythrocyte stromata leads to typical skin sensitization of the contact type towards the respective simple chemicals, namely picryl chloride or 2,4-dinitrofluorobenzene. Therefore such sensitivity can be brought about not only by low molecular chemical compounds but by a material which must be regarded as a typical antigen.

Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Landsteiner K
Laboratories of The Rockefeller Institute for Medical Research.
Chase M W
References (7)
7 references, click to expand
  1. THE EFFECT OF ANTECEDENT INFECTION AND IMMUNIZATION WITH STREPTOCOCCI UPON THE REACTIVITY OF RABBITS TO HORSE SERUM.
    J Exp Med. 1934 Aug 31;60(3):323-37 PMID: 19870304
  2. STUDIES ON THE SENSITIZATION OF ANIMALS WITH SIMPLE CHEMICAL COMPOUNDS : IV. ANAPHYLAXIS INDUCED BY PICRYL CHLORIDE AND 2:4 DINITROCHLOROBENZENE.
    J Exp Med. 1937 Aug 31;66(3):337-51 PMID: 19870667
  3. ON CROSS REACTIONS OF IMMUNE SERA TO AZOPROTEINS.
    J Exp Med. 1936 Feb 29;63(3):325-39 PMID: 19870475
  4. STUDIES ON THE SENSITIZATION OF ANIMALS WITH SIMPLE CHEMICAL COMPOUNDS : VIII. SENSITIZATION TO PICRIC ACID; SUBSIDIARY AGENTS AND MODE OF SENSITIZATION.
    J Exp Med. 1940 Sep 30;72(4):361-6 PMID: 19871030
  5. STUDIES ON THE SENSITIZATION OF ANIMALS WITH SIMPLE CHEMICAL COMPOUNDS : VII. SKIN SENSITIZATION BY INTRAPERITONEAL INJECTIONS.
    J Exp Med. 1940 Jan 31;71(2):237-45 PMID: 19870959
  6. STUDIES ON THE SENSITIZATION OF ANIMALS WITH SIMPLE CHEMICAL COMPOUNDS. II.
    J Exp Med. 1936 Sep 30;64(4):625-39 PMID: 19870557
  7. STUDIES ON THE SENSITIZATION OF ANIMALS WITH SIMPLE CHEMICAL COMPOUNDS.
    J Exp Med. 1935 Apr 30;61(5):643-56 PMID: 19870383
Article Info
Journal
The Journal of experimental medicine
Abbr.
J Exp Med
ISSN
0022-1007
Published
1941-02-28
Pages
431-8
Language
English
Region
United States
NLM ID
2985109R
PMCID
PMC2135139
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