SOME CONSTITUENTS OF ELEMENTARY BODIES OF VACCINIA.

The Journal of experimental medicine ·Vol. 71 ·No. 3 ·1940-02-29 ·Pages 373-89

Smadel JE, Lavin GI, Dubos RJ

Abstract

Treatment of elementary bodies of vaccinia with dilute solutions of sodium hydroxide resulted in the extraction of certain soluble materials accounting for half of the dry weight of the virus. Elementary bodies contained about 0.4 per cent inorganic phosphorus, practically all of which occurred in the form of a nucleoprotein containing thymus nucleic acid. In addition, a substance was recovered that reacted with S antibodies. From past experience one is led to believe that S antigen, as ordinarily encountered, is a protein which is not in combination with nucleic acid.

Authors & Affiliations

3 authors, click to expand affiliations / ORCID

Smadel J E

Hospital and the Laboratories of The Rockefeller Institute for Medical Research.

Lavin G I

Dubos R J

References (12)

12 references, click to expand

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Article Info

Journal

The Journal of experimental medicine

Abbr.

J Exp Med

ISSN

0022-1007

DOI

10.1084/jem.71.3.373

Published

1940-02-29

Pages

373-89

Language

English

Region

United States

NLM ID

2985109R

PMCID

PMC2134988

External Links

PubMed source DOI: 10.1084/jem.71.3.373 PMC Full Text View journal details

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