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PMID: 19870902 Published · ppublish English Journal Article

NEUTRALIZATION OF EPIDEMIC INFLUENZA VIRUS : THE LINEAR RELATIONSHIP BETWEEN THE QUANTITY OF SERUM AND THE QUANTITY OF VIRUS NEUTRALIZED.

The Journal of experimental medicine ·Vol. 70 ·No. 2 ·1939-07-31 ·Pages 209-22

Horsfall FL

Abstract

A linear relationship exists between the logarithm of the quantity of epidemic influenza virus neutralized and the logarithm of the quantity of antiserum which is capable of achieving this result. This relationship is the same for the serum of a ferret convalescent from experimental influenza as for the serum of a rabbit immunized with the virus. By means of the linear relationship between virus and antiserum it is possible to determine a fixed, rather than a relative, value for the neutralizing capacity of a serum.

Authors & Affiliations
1 authors, click to expand affiliations / ORCID
Horsfall F L
Laboratories of the International Health Division of The Rockefeller Foundation, New York.
References (3)
3 references, click to expand
  1. TRANSMISSION OF INFLUENZA BY A FILTERABLE VIRUS.
    Science. 1934 Nov 16;80(2081):457-9 PMID: 17795179
  2. Etiological and Serological Studies in Epidemic Influenza.
    Am J Public Health Nations Health. 1937 Nov;27(11):1141-60 PMID: 18014734
  3. THE INCIDENCE OF NEUTRALIZING ANTIBODIES FOR HUMAN INFLUENZA VIRUS IN THE SERUM OF HUMAN INDIVIDUALS OF DIFFERENT AGES.
    J Exp Med. 1936 Apr 30;63(5):655-68 PMID: 19870495
Article Info
Journal
The Journal of experimental medicine
Abbr.
J Exp Med
ISSN
0022-1007
Published
1939-07-31
Pages
209-22
Language
English
Region
United States
NLM ID
2985109R
PMCID
PMC2133786
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