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PMID: 19870821 Published · ppublish English Journal Article

CELLULAR REACTIONS TO TUBERCULO-PROTEINS COMPARED WITH THE REACTIONS TO TUBERCULO-LIPIDS.

The Journal of experimental medicine ·Vol. 68 ·No. 6 ·1938-10-31 ·Pages 837-52

Sabin FR

Abstract

1. Tuberculo-protein in solution induces the formation of monocytes in the normal animal and tubercles of epithelioid cells in that which is tuberculous. 2. Freshly precipitated tuberculo-proteins from the culture media and from the bacilli induce a moderate formation of epithelioid cells in normal animals, and more in the tuberculous. 3. Insoluble forms of tuberculo-protein induce complex tubercular tissue in normal animals. This action is enhanced in the tuberculous.

Authors & Affiliations
1 authors, click to expand affiliations / ORCID
Sabin F R
Laboratories of The Rockefeller Institute for Medical Research.
References (7)
7 references, click to expand
  1. THE CELLULAR REACTIONS TO LIPOID FRACTIONS FROM ACID-FAST BACILLI.
    J Exp Med. 1932 Nov 30;56(6):867-91 PMID: 19870109
  2. CELLULAR REACTIONS TO WAX-LIKE MATERIALS FROM ACID-FAST BACTERIA : THE UNSAPONIFIABLE FRACTION FROM THE TUBERCLE BACILLUS, STRAIN H-37.
    J Exp Med. 1935 Nov 30;62(6):751-69 PMID: 19870446
  3. THE FUNDAMENTAL PROPERTIES OF THE FIBROBLAST AND THE MACROPHAGE : II. THE MACROPHAGE.
    J Exp Med. 1926 Aug 31;44(3):285-305 PMID: 19869185
  4. BIOLOGICAL STUDIES OF THE TUBERCLE BACILLUS : II. A NEW CONCEPTION OF THE PATHOLOGY OF EXPERIMENTAL AVIAN TUBERCULOSIS WITH SPECIAL REFERENCE TO THE DISEASE PRODUCED BY DISSOCIATED VARIANTS.
    J Exp Med. 1933 Jan 31;57(2):239-64 PMID: 19870129
  5. THE ORIGIN AND FATE OF TWO TYPES OF MULTI-NUCLEATED GIANT CELLS IN THE CIRCULATING BLOOD.
    J Exp Med. 1930 Jul 31;52(2):279-97 PMID: 19869765
  6. TUBERCULAR ALLERGY WITHOUT INFECTION.
    J Exp Med. 1938 Oct 31;68(5):659-76 PMID: 19870809
  7. REACTIONS OF NORMAL AND TUBERCULOUS ANIMALS TO TUBERCULO-PROTEIN AND TUBERCULO-PHOSPHATIDE.
    J Exp Med. 1938 Oct 31;68(5):641-58 PMID: 19870808
Article Info
Journal
The Journal of experimental medicine
Abbr.
J Exp Med
ISSN
0022-1007
Published
1938-10-31
Pages
837-52
Language
English
Region
United States
NLM ID
2985109R
PMCID
PMC2133709
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