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PMID: 19870794 Published · ppublish English Journal Article

THE EFFECT OF THE PULSE ON THE SPREAD OF SUBSTANCES THROUGH TISSUES.

The Journal of experimental medicine ·Vol. 68 ·No. 3 ·1938-08-31 ·Pages 377-400

McMaster PD, Parsons RJ

Abstract

The pulsation of blood vessels in the ear of the rabbit greatly increases the rate of the spread of dye introduced into the subcutaneous tissue. The appearance of edema in tissues perfused at a constant pressure leads to very little increase in the rate of dye spread. By contrast, a rapid interstitial spread of dye occurs in tissues becoming edematous while perfused with a pulsatile flow of blood. The significance of these facts is discussed.

Authors & Affiliations
2 authors, click to expand affiliations / ORCID
McMaster P D
Laboratories of The Rockefeller Institute for Medical Research.
Parsons R J
References (7)
7 references, click to expand
  1. I. THE PERMEABILITY OF THE WALL OF THE LYMPHATIC CAPILLARY.
    J Exp Med. 1932 Jul 31;56(2):223-38 PMID: 19870062
  2. THE PARTICIPATION OF SKIN LYMPHATICS IN REPAIR OF THE LESIONS DUE TO INCISIONS AND BURNS.
    J Exp Med. 1934 Sep 30;60(4):479-501 PMID: 19870317
  3. THE LYMPHATIC PARTICIPATION IN HUMAN CUTANEOUS PHENOMENA : A STUDY OF THE MINUTE LYMPHATICS OF THE LIVING SKIN.
    J Exp Med. 1933 Apr 30;57(5):751-74 PMID: 19870160
  4. II. INDUCED ALTERATIONS IN THE PERMEABILITY OF THE LYMPHATIC CAPILLARY.
    J Exp Med. 1932 Jul 31;56(2):239-53 PMID: 19870063
  5. CHANGES IN THE CUTANEOUS LYMPHATICS OF HUMAN BEINGS AND IN THE LYMPH FLOW UNDER NORMAL AND PATHOLOGICAL CONDITIONS.
    J Exp Med. 1937 Feb 28;65(3):347-72 PMID: 19870606
  6. THE LYMPHATICS AND LYMPH FLOW IN THE EDEMATOUS SKIN OF HUMAN BEINGS WITH CARDIAC AND RENAL DISEASE.
    J Exp Med. 1937 Feb 28;65(3):373-92 PMID: 19870607
  7. THE EFFECT OF THE PULSE UPON THE FORMATION AND FLOW OF LYMPH.
    J Exp Med. 1938 Aug 31;68(3):353-76 PMID: 19870793
Article Info
Journal
The Journal of experimental medicine
Abbr.
J Exp Med
ISSN
0022-1007
Published
1938-08-31
Pages
377-400
Language
English
Region
United States
NLM ID
2985109R
PMCID
PMC2133676
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