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PMID: 19870621 Published · ppublish English Journal Article

STUDIES ON THE SEROLOGICAL TYPING OF STREPTOCOCCUS HEMOLYTICUS.

The Journal of experimental medicine ·Vol. 65 ·No. 4 ·1937-03-31 ·Pages 595-612

Pauli RH, Coburn AF, Assistance of Florence Stone, Ph.D

Abstract

The cross-reactions which interfere with satisfactory serological identification of hemolytic streptococcus are due to anticarbohydrate in the sera used for typing. This antibody can be removed easily by absorption with purified streptococcus carbohydrate, and type identification is then readily established. The serological classification of hemolytic streptococcus from throat infections contracted in New York during 1935 and 1936 showed the predominance of types 4, 13 and 22. Type 13 appeared to be the most serious in initiating rheumatic activity during this period of observation.

Authors & Affiliations
3 authors, click to expand affiliations / ORCID
Pauli R H
Department of Medicine, College of Physicians and Surgeons, Columbia University, and the Presbyterian Hospital, New York.
Coburn A F
Assistance of Florence Stone, Ph.D
References (3)
3 references, click to expand
  1. STUDIES ON THE IMMUNE RESPONSE OF THE RHEUMATIC SUBJECT AND ITS RELATIONSHIP TO ACTIVITY OF THE RHEUMATIC PROCESS. IV. CHARACTERISTICS OF STRAINS OF HEMOLYTIC STREPTOCOCCUS, EFFECTIVE AND NON-EFFECTIVE IN INITIATING RHEUMATIC ACTIVITY.
    J Clin Invest. 1935 Nov;14(6):755-62 PMID: 16694345
  2. STUDIES ON THE BIOLOGY OF STREPTOCOCCUS : I. ANTIGENIC RELATIONSHIPS BETWEEN STRAINS OF STREPTOCOCCUS HAEMOLYTICUS.
    J Exp Med. 1919 Sep 1;30(3):179-213 PMID: 19868354
  3. STUDIES ON THE RELATIONSHIP OF STREPTOCOCCUS HEMOLYTICUS TO THE RHEUMATIC PROCESS : II. OBSERVATIONS ON THE BIOLOGICAL CHARACTER OF STREPTOCOCCUS HEMOLYTICUS ASSOCIATED WITH RHEUMATIC DISEASE.
    J Exp Med. 1932 Oct 31;56(5):633-50 PMID: 19870090
Article Info
Journal
The Journal of experimental medicine
Abbr.
J Exp Med
ISSN
0022-1007
Published
1937-03-31
Pages
595-612
Language
English
Region
United States
NLM ID
2985109R
PMCID
PMC2133507
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