STUDIES ON THE CULTIVATION OF THE TYPHUS FEVER RICKETTSIA IN THE PRESENCE OF LIVE TISSUE.

The Journal of experimental medicine ·Vol. 55 ·No. 4 ·1932-03-31 ·Pages 563-76

Nigg C, Landsteiner K

Abstract

1. Rickettsia prowazeki can be cultivated for many generations in vitro, without diminution in numbers or virulence, in media similar to those described by Maitland, Rivers, and others for the cultivation of certain viruses. In all probability, such cultures can be maintained indefinitely. 2. It has been impossible, thus far, to cultivate the typhus rickettsia without employing living tissue.

Authors & Affiliations

2 authors, click to expand affiliations / ORCID

Nigg C

Laboratories of The Rockefeller Institute for Medical Research.

Landsteiner K

References (8)

8 references, click to expand

OBSERVATIONS CONCERNING THE PERSISTENCE OF LIVING CELLS IN MAITLAND'S MEDIUM FOR THE CULTIVATION OF VACCINE VIRUS.
J Exp Med. 1929 Jul 31;50(2):181-7 PMID: 19869613
TYPHUS FEVER : I. COMPARATIVE STUDY OF EUROPEAN AND AMERICAN TYPHUS IN LABORATORY ANIMALS.
J Exp Med. 1931 Jul 31;54(2):181-6 PMID: 19869908
DEVELOPMENT IN TISSUE CULTURES OF THE INTRACELLULAR CHANGES CHARACTERISTIC OF VACCINAL AND HERPETIC INFECTIONS.
J Exp Med. 1929 Oct 31;50(5):665-72 PMID: 19869653
The Cultivation of the Micro-Organisms of Rocky Mountain spotted Fever (Dermacentroxenus Rickettsi) and of Typhus (Rickettsia Prowazeki) in Tissue Cultures.
J Med Res. 1923 Dec;44(2):231-256.1 PMID: 19972597
STUDIES ON MEXICAN TYPHUS FEVER. I.
J Exp Med. 1930 May 31;51(6):847-58 PMID: 19869731
THE GROWTH AND DEATH OF TISSUE CULTURES EXPOSED TO SUPRANORMAL TEMPERATURES.
J Exp Med. 1931 Jul 31;54(3):323-32 PMID: 19869920
TYPHUS FEVER : III. THE BEHAVIOR OF RICKETTSIA PROWAZEKI IN TISSUE CULTURES.
J Exp Med. 1931 Jul 31;54(3):307-14 PMID: 19869918
CULTIVATION OF VACCINE VIRUS.
J Exp Med. 1930 Sep 30;52(4):465-70 PMID: 19869779

Article Info

Journal

The Journal of experimental medicine

Abbr.

J Exp Med

ISSN

0022-1007

DOI

10.1084/jem.55.4.563

Published

1932-03-31

Pages

563-76

Language

English

Region

United States

NLM ID

2985109R

PMCID

PMC2132120

External Links

PubMed source DOI: 10.1084/jem.55.4.563 PMC Full Text View journal details

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STUDIES ON THE CULTIVATION OF THE TYPHUS FEVER RICKETTSIA IN THE PRESENCE OF LIVE TISSUE.

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