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PMID: 19869827 Published · ppublish English Journal Article

THE EFFECT OF TESTICULAR EXTRACT ON FILTERABLE VIRUSES.

The Journal of experimental medicine ·Vol. 53 ·No. 1 ·1931-01-01 ·Pages 43-50

Hoffman DC

Abstract

The Reynals factor promotes the pathogenic action of the viruses of herpes, vesicular stomatitis of horses, Borna disease, and vaccinia. The heightening of virulence is revealed in various ways. The effects of the viruses may be accentuated; or a weak strain converted into a strong one, as in the case of the F. strain of herpes virus; or the power acquired to infect resistant species or tissues, as, e.g., rabbits and the abdominal skin of guinea pigs, with acute vesicular stomatitis. The Reynals factor should serve as an important agent in the study of filterable viruses.

Authors & Affiliations
1 authors, click to expand affiliations / ORCID
Hoffman D C
Laboratories of The Rockefeller Institute for Medical Research.
References (5)
5 references, click to expand
  1. THE ACTION OF TESTICLE, KIDNEY, AND SPLEEN EXTRACTS ON THE INFECTIVE POWER OF BACTERIA.
    J Exp Med. 1931 Jan 1;53(1):37-42 PMID: 19869826
  2. PHYSICAL, CHEMICAL, AND BIOLOGICAL STUDIES ON THE VIRUS OF VESICULAR STOMATITIS OF HORSES : COMPARISON WITH THE VIRUS OF FOOT-AND-MOUTH DISEASE.
    J Exp Med. 1927 May 31;45(6):969-81 PMID: 19869312
  3. THE EFFECT OF EXTRACTS OF CERTAIN ORGANS FROM NORMAL AND IMMUNIZED ANIMALS ON THE INFECTING POWER OF VACCINE VIRUS.
    J Exp Med. 1929 Aug 31;50(3):327-40 PMID: 19869626
  4. CONTRIBUTIONS TO THE PATHOLOGY OF EXPERIMENTAL VIRUS ENCEPHALITIS : III. VARIETIES AND PROPERTIES OF THE HERPES VIRUS.
    J Exp Med. 1925 Feb 28;41(3):357-77 PMID: 19868994
  5. A STUDY OF THE GENERALIZATION OF VACCINE VIRUS FROM ENHANCED SKIN LESIONS.
    J Exp Med. 1929 Aug 31;50(3):341-53 PMID: 19869627
Article Info
Journal
The Journal of experimental medicine
Abbr.
J Exp Med
ISSN
0022-1007
Published
1931-01-01
Pages
43-50
Language
English
Region
United States
NLM ID
2985109R
PMCID
PMC2131937
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