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PMID: 19868959 Published · ppublish English Journal Article

A FILTERABLE VIRUS INFECTION OF RABBITS : II. ITS OCCURRENCE IN APPARENTLY NORMAL RABBITS.

The Journal of experimental medicine ·Vol. 40 ·No. 6 ·1924-11-30 ·Pages 789-96

Andrewes CH, Miller CP

Abstract

1. In two, and possibly four, of six transmission series of rabbits inoculated in the beginning with the blood of apparently normal rabbits a virus was recovered having the same properties as that recovered from series originally inoculated with material from rheumatic fever patients. The virus was immunologically identical with Rivers-Tillett Virus III and with that obtained from the rheumatic fever series. In conducting the control series precautions were taken to prevent infection of rabbit stock from known sources of the virus. 2. Treating rabbits with benzene does not appreciably increase their susceptibility to infection with the virus. 3. The virus is probably a parasite of the domestic rabbit but up to the present time the natural course of the infection in that animal is unknown.

Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Andrewes C H
Hospital of The Rockefeller Institute for Medical Research.
Miller C P
References (5)
5 references, click to expand
  1. Experimental Production of Herpetic Lesions in Organs and Tissues of the Rabbit.
    J Med Res. 1923 Dec;44(2):121-138.5 PMID: 19972592
  2. FURTHER OBSERVATIONS ON THE PHENOMENA ENCOUNTERED IN ATTEMPTING TO TRANSMIT VARICELLA TO RABBITS.
    J Exp Med. 1924 May 31;39(6):777-802 PMID: 19868883
  3. PURE CULTIVATION IN VIVO OF VACCINE VIRUS FREE FROM BACTERIA.
    J Exp Med. 1915 Jun 1;21(6):539-70 PMID: 19867889
  4. STUDIES ON VARICELLA : THE SUSCEPTIBILITY OF RABBITS TO THE VIRUS OF VARICELLA.
    J Exp Med. 1923 Nov 30;38(6):673-90 PMID: 19868818
  5. A FILTERABLE VIRUS INFECTION OF RABBITS : I. ITS OCCURRENCE IN ANIMALS INOCULATED WITH RHEUMATIC FEVER MATERIAL.
    J Exp Med. 1924 Nov 30;40(6):773-87 PMID: 19868958
Article Info
Journal
The Journal of experimental medicine
Abbr.
J Exp Med
ISSN
0022-1007
Published
1924-11-30
Pages
789-96
Language
English
Region
United States
NLM ID
2985109R
PMCID
PMC2128602
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