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PMID: 19867465 Published · ppublish English Journal Article

METHOD FOR THE PURE CULTIVATION OF PATHOGENIC TREPONEMA PALLIDUM (SPIROCHAETA PALLIDA).

The Journal of experimental medicine ·Vol. 14 ·No. 2 ·1911-08-01 ·Pages 99-108

Noguchi H

Abstract

In conclusion, it may be pointed out that this is the first time that Treponema pallidum of Schaudinn has been proven beyond all doubt to have been obtained in pure culture. The method of cultivation described would appear also to be suitable for obtaining indefinite generations of the microorganism. Doubtless slight modifications will adapt it to a larger number of strains and possibly to the cultivation of all strains and to still other species of treponema. Finally, it may now be accepted as established that the testicular lesions produced in rabbits by means of syphilitic materials are the result of the multiplication of the pallida and not of some associated indefinite parasite.

Authors & Affiliations
1 authors, click to expand affiliations / ORCID
Noguchi H
Laboratories of the Rockefeller Institute for Medical Research, New York.
Article Info
Journal
The Journal of experimental medicine
Abbr.
J Exp Med
ISSN
0022-1007
Published
1911-08-01
Pages
99-108
Language
English
Region
United States
NLM ID
2985109R
PMCID
PMC2124905
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