Growth signaling at the nexus of stem cell life and death.
作者:
Wood(Kris C),Sabatini(David M)
状态:
发布时间2009-09-07
, 更新时间 2016-10-25
期刊:
Cell Stem Cell
摘要:
Stress can activate tumor-suppressive mechanisms, causing the loss of adult stem cell function with age. In this issue of Cell Stem Cell and in Nature, Castilho et al. (2009) and Harrison et al. (2009) highlight the importance of mTOR signaling in stem cell exhaustion and mammalian aging, respectively.