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题目:: A molecular link between AKT regulation and chemotherapeutic response.
作者:: Dibble(Christian C),Manning(Brendan D)
状态:: 发布时间2009-09-07 , 更新时间 2016-11-22
期刊:: Cancer Cell
摘要:: The protein kinase AKT is frequently activated in human cancers and has been implicated in resistance to chemotherapy. In this issue of Cancer Cell, Pei et al. show that FKBP51 negatively regulates AKT through the phosphatase PHLPP. This regulation appears to be a determinant of chemosensitivity in cancer cells.
语言:: eng
DOI:: 10.1016/j.ccr.2009.08.011

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