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PMID: 196571 Published · ppublish English Comparative Study Journal Article

Further studies on human enteric coronaviruses.

Archives of virology ·Vol. 54 ·No. 1-2 ·1977-00-00 ·Pages 107-17

Caul EO, Egglestone SI

Abstract

Comparisons were made between human enteric coronaviruses and the enteric coronaviruses of pigs and calves by negative staining. Examination of human intestinal organ culture fluids at various time intervals after inoculation with the human enteric coronavirus showed increasing numbers of particles in the fluids. Thin sections of the columnar epithelial cells of these explants showed a number of features consistent with the replication of known human and animal coronaviruses. Virus particles found in thin sections had a mean diameter of 68 nm. In addition, a structure was found in thin sections which has not been described previously. This structure may represent the viral nucleocapsid.

MeSH Terms
Animals Cattle Coronaviridae/growth & development,ultrastructure Culture Media Cytoplasm/microbiology Diarrhea Viruses, Bovine Viral/ultrastructure Feces/microbiology Gastroenteritis/microbiology Humans Inclusion Bodies, Viral Organ Culture Techniques Swine Transmissible gastroenteritis virus/ultrastructure Virus Replication
Chemicals
Culture Media
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Caul E O
Egglestone S I
References (16)
16 references, click to expand
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Article Info
Journal
Archives of virology
Abbr.
Arch Virol
ISSN
0304-8608
Published
1977-00-00
Pages
107-17
Language
English
Region
Austria
NLM ID
7506870
PMCID
PMC7087196
Subset
IM
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