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题目:: Biology of glioma cancer stem cells.
作者:: Park(Deric M),Rich(Jeremy N)
状态:: 发布时间2009-08-27 , 更新时间 2016-11-25
期刊:: Mol Cells
摘要:: Gliomas, much like other cancers, are composed of a heterogeneous mix of neoplastic and non-neoplastic cells that include both native and recruited cells. There is extensive diversity among the tumor cells, with differing capacity for in vitro and in vivo growth, a property intimately linked to the cell's differentiation status. Those cells that are undifferentiated, self-renewing, with the capacity for developing tumors (tumorigenic) cells are designated by some as cancer stem cells, because of the stem-like properties. These cells may be a critical therapeutic target. However the exact identity and cell(s) of origin of the so-called glioma cancer stem cell remain elusive. Here we review the current understanding of glioma cancer stem cell biology.
语言:: eng
DOI:: 10.1007/s10059-009-0111-2

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