ShortRead is a package for input, quality assessment, manipulation and output of high-throughput sequencing data. ShortRead is provided in the R and Bioconductor environments, allowing ready access to additional facilities for advanced statistical analysis, data transformation, visualization and integration with diverse genomic resources. This package is implemented in R and available at the Bioconductor web site; the package contains a 'vignette' outlining typical work flows.
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