Home LiteratureArticle Details
PMID: 19639026 Published · ppublish English Comment News

Elucidating the role of 8q24 in colorectal cancer.

Nature genetics ·Vol. 41 ·No. 8 ·2009-08-00 ·Pages 868-9

Harismendy O, Frazer KA

Abstract

暂无摘要

MeSH Terms
Animals Chromosomes, Human, Pair 8/genetics Colorectal Neoplasms/genetics Genetic Predisposition to Disease Humans Mice Polymorphism, Single Nucleotide/genetics Proto-Oncogene Proteins c-myc/genetics,metabolism TCF Transcription Factors/metabolism Transcription Factor 7-Like 2 Protein Wnt Proteins/metabolism
Chemicals
Proto-Oncogene Proteins c-myc TCF Transcription Factors TCF7L2 protein, human Tcf7l2 protein, mouse Transcription Factor 7-Like 2 Protein Wnt Proteins
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Harismendy Olivier
Scripps Genomic Medicine, Scripps Translational Science Institute and the Scripps Research Institute, La Jolla, California, USA.
Frazer Kelly A
References (15)
15 references, click to expand
  1. A common genetic risk factor for colorectal and prostate cancer.
    Nat Genet. 2007 Aug;39(8):954-6 PMID: 17618282
  2. A susceptibility locus for papillary thyroid carcinoma on chromosome 8q24.
    Cancer Res. 2009 Jan 15;69(2):625-31 PMID: 19147577
  3. The 8q24 cancer risk variant rs6983267 shows long-range interaction with MYC in colorectal cancer.
    Nat Genet. 2009 Aug;41(8):882-4 PMID: 19561607
  4. A range of cancers is associated with the rs6983267 marker on chromosome 8.
    Cancer Res. 2008 Dec 1;68(23):9982-6 PMID: 19047180
  5. The common colorectal cancer predisposition SNP rs6983267 at chromosome 8q24 confers potential to enhanced Wnt signaling.
    Nat Genet. 2009 Aug;41(8):885-90 PMID: 19561604
  6. Capturing chromosome conformation.
    Science. 2002 Feb 15;295(5558):1306-11 PMID: 11847345
  7. Human genetic variation and its contribution to complex traits.
    Nat Rev Genet. 2009 Apr;10(4):241-51 PMID: 19293820
  8. Genome-wide association scan identifies a colorectal cancer susceptibility locus on chromosome 8q24.
    Nat Genet. 2007 Aug;39(8):989-94 PMID: 17618283
  9. Genetic variation in 8q24 associated with risk of colorectal cancer.
    Cancer Biol Ther. 2007 Jul;6(7):1143-7 PMID: 17630503
  10. A genome-wide association scan of tag SNPs identifies a susceptibility variant for colorectal cancer at 8q24.21.
    Nat Genet. 2007 Aug;39(8):984-8 PMID: 17618284
  11. Linking colorectal cancer to Wnt signaling.
    Cell. 2000 Oct 13;103(2):311-20 PMID: 11057903
  12. Sequence variant on 8q24 confers susceptibility to urinary bladder cancer.
    Nat Genet. 2008 Nov;40(11):1307-12 PMID: 18794855
  13. Comprehensive resequence analysis of a 136 kb region of human chromosome 8q24 associated with prostate and colon cancers.
    Hum Genet. 2008 Sep;124(2):161-70 PMID: 18704501
  14. Multiple newly identified loci associated with prostate cancer susceptibility.
    Nat Genet. 2008 Mar;40(3):316-21 PMID: 18264097
  15. Oncogenes and cancer.
    N Engl J Med. 2008 Jan 31;358(5):502-11 PMID: 18234754
Article Info
Journal
Nature genetics
Abbr.
Nat Genet
ISSN
1546-1718
Published
2009-08-00
Pages
868-9
Language
English
Region
United States
NLM ID
9216904
Subset
IM
Corrections
ErratumIn
-
CommentOn
CommentOn
Analysis Services
Analysis Services

Contact

No. 2 Wenbo Road, Zhangqiu District, Jinan, Shandong

Qilu Normal University · Genelibs Bioinformatics Lab

750 Shunhua Rd, Jinan

2F, Bldg F, University Science Park

Tel: 0531-88819269

WeChat Official Account

Follow our WeChat subscription account for real-time updates and the latest in medical and biological research.


Business Email

E-mail: product@genelibs.com