Stem cell aging and aberrant differentiation within the niche.
作者:
Choi(Jinkuk),Artandi(Steven)
状态:
发布时间2009-07-02
, 更新时间 2016-05-18
期刊:
Cell Stem Cell
摘要:
Stem cells age, but the underlying mechanisms remain unclear. In a recent issue of Cell, Inomata and colleagues (2009) show that DNA damage, a prime suspect in stem cell aging, causes graying and loss of melanocyte stem cells by inducing premature differentiation, without inducing apoptosis or senescence.