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PMID: 19458784 Published · ppublish English Journal Article

Variable selection for multivariate failure time data.

Biometrika ·Vol. 92 ·No. 2 ·2005-00-00 ·Pages 303-316

Cai J, Fan J, Li R, Zhou H

Abstract

In this paper, we proposed a penalised pseudo-partial likelihood method for variable selection with multivariate failure time data with a growing number of regression coefficients. Under certain regularity conditions, we show the consistency and asymptotic normality of the penalised likelihood estimators. We further demonstrate that, for certain penalty functions with proper choices of regularisation parameters, the resulting estimator can correctly identify the true model, as if it were known in advance. Based on a simple approximation of the penalty function, the proposed method can be easily carried out with the Newton-Raphson algorithm. We conduct extensive Monte Carlo simulation studies to assess the finite sample performance of the proposed procedures. We illustrate the proposed method by analysing a dataset from the Framingham Heart Study.

Authors & Affiliations
4 authors, click to expand affiliations / ORCID
Cai Jianwen
Department of Biostatistics, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599-7420, U.S.A., cai@bios.unc.edu.
Fan Jianqing
Li Runze
Zhou Haibo
References (7)
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Article Info
Journal
Biometrika
Abbr.
Biometrika
ISSN
0006-3444
Published
2005-00-00
Pages
303-316
Language
English
Region
England
NLM ID
0413661
PMCID
PMC2674767
Grants
NIDA NIH HHS · P50 DA010075 · United States
NIDA NIH HHS · P50 DA010075-100008 · United States
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