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PMID: 19412437 Published · ppublish English Journal Article

Patterns of insertion and deletion in Mammalian genomes.

Current genomics ·Vol. 8 ·No. 6 ·2007-09-00 ·Pages 370-8

Fan Y, Wang W, Ma G, Liang L, Shi Q, Tao S

Abstract

Nucleotide insertions and deletions (indels) are responsible for gaps in the sequence alignments. Indel is one of the major sources of evolutionary change at the molecular level. We have examined the patterns of insertions and deletions in the 19 mammalian genomes, and found that deletion events are more common than insertions in the mammalian genomes. Both the number of insertions and deletions decrease rapidly when the gap length increases and single nucleotide indel is the most frequent in all indel events. The frequencies of both insertions and deletions can be described well by power law.

Keywords
Insertion deletion gap indel mammalian genome.
Authors & Affiliations
6 authors, click to expand affiliations / ORCID
Fan Yanhui
Bioinformatics Center, College of Life Science, Northwest A&F University, Yangling, Shaanxi 712100, China.
Wang Wenjuan
Ma Guoji
Liang Lijing
Shi Qi
Tao Shiheng
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Article Info
Journal
Current genomics
Abbr.
Curr Genomics
ISSN
1389-2029
DOI
10.2174/138920207783406479
Published
2007-09-00
Pages
370-8
Language
English
Region
United Arab Emirates
NLM ID
100960527
PMCID
PMC2671719
External Links
PubMed source DOI: 10.2174/138920207783406479 PMC Full Text View journal details
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