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题目:: Bringing up the rear: defining the roles of the uropod.
作者:: Sánchez-Madrid(Francisco),Serrador(Juan M)
状态:: 发布时间2009-04-23 , 更新时间 2009-11-19
期刊:: Nat Rev Mol Cell Biol
摘要:: Renewed interest in cell shape has been prompted by a recent flood of evidence that indicates that cell polarity is essential for the biology of motile cells. The uropod, a protrusion at the rear of amoeboid motile cells such as leukocytes, exemplifies the importance of morphology in cell motility. Remodelling of cell shape by uropod-interfering agents disturbs cell migration. But even though the mechanisms by which uropods regulate cell migration are beginning to emerge, their functional significance remains enigmatic.
语言:: eng
DOI:: 10.1038/nrm2680

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