Home LiteratureArticle Details
PMID: 1934121 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't

Pheromone production and response in sterile mutants of fission yeast.

Current genetics ·Vol. 20 ·No. 1-2 ·1991-07-00 ·Pages 79-85

Leupold U, Sipiczki M, Egel R

Abstract

Genetically heterothallic strains of various sterile mutants were assayed for residual production of the corresponding mating pheromone as well as responsiveness towards the opposite pheromone. No sexual activities were detected in ste11 strains (previously referred to as aff1 or steX, which we show are allelic), whilst the production of M factor was unaffected by ste1 to ste10 mutations. P factor production was still possible in class I ste mutants (ste5, ste6 and ste10), which also allow meiosis in diploid strains. With the exception of the leaky ste10-F23 mutant, no changes in cell morphology were induced by exposure to the opposite pheromone in the ste mutant strains.

Related Genes
MeSH Terms
Alleles Conjugation, Genetic Diploidy Genes, Fungal Meiosis Mutation Pheromones/biosynthesis Schizosaccharomyces/genetics
Chemicals
Pheromones
Authors & Affiliations
3 authors, click to expand affiliations / ORCID
Leupold U
Institute of General Microbiology, University of Bern, Switzerland.
Sipiczki M
Egel R
References (24)
24 references, click to expand
  1. Genes involved in mating type expression of fission yeast.
    Mol Gen Genet. 1973 May 28;122(4):339-43 PMID: 4716873
  2. Schizosaccharomyces pombe ras1 and byr1 are functionally related genes of the ste family that affect starvation-induced transcription of mating-type genes.
    Mol Cell Biol. 1990 Feb;10(2):549-60 PMID: 2300054
  3. Sterile mutants of Schizosaccharomyces pombe: Analysis by somatic hybridization.
    Curr Genet. 1982 Dec;6(3):223-7 PMID: 24186549
  4. The S.pombe mei2 gene encoding a crucial molecule for commitment to meiosis is under the regulation of cAMP.
    EMBO J. 1988 Mar;7(3):761-7 PMID: 2840284
  5. Involvement of ras in sexual differentiation but not in growth control in fission yeast.
    EMBO J. 1986 Nov;5(11):2963-71 PMID: 16453723
  6. Sexual differentiation in fission yeast.
    Trends Genet. 1990 Nov;6(11):369-73 PMID: 2087776
  7. The pat1 protein kinase controls transcription of the mating-type genes in fission yeast.
    EMBO J. 1990 May;9(5):1401-6 PMID: 2328719
  8. Initiation of meiotic recombination by double-strand DNA breaks in S. pombe.
    Cell. 1986 Aug 29;46(5):725-31 PMID: 3742597
  9. Frequency of mating-type switching in homothallic fission yeast.
    Nature. 1977 Mar 10;266(5598):172-4 PMID: 859590
  10. Negative control for the initiation of meiosis in Schizosaccharomyces pombe.
    Proc Natl Acad Sci U S A. 1985 Apr;82(8):2447-51 PMID: 16593556
  11. Mutants of Schizosaccharomyces pombe which sporulate in the haploid state.
    Mol Gen Genet. 1985;198(3):416-21 PMID: 25864229
  12. Isolation and characterization of Schizosaccharomyces pombe mutants phenotypically similar to ras1-.
    Mol Gen Genet. 1988 Dec;215(1):26-31 PMID: 3071741
  13. Characterization of the Schizosaccharomyces pombe ral2 gene implicated in activation of the ras1 gene product.
    Mol Cell Biol. 1989 Dec;9(12):5617-22 PMID: 2586528
  14. The product of the mei3+ gene, expressed under control of the mating-type locus, induces meiosis and sporulation in fission yeast.
    EMBO J. 1987 Mar;6(3):729-36 PMID: 3034608
  15. Mapping of the ras1 gene of Schizosaccharomyces pombe.
    Mol Gen Genet. 1987 Oct;209(3):627-9 PMID: 3481018
  16. A specific inhibitor of the ran1+ protein kinase regulates entry into meiosis in Schizosaccharomyces pombe.
    Nature. 1988 Apr 7;332(6164):509-14 PMID: 3357510
  17. Genetical analysis of a sterile mutant by protoplast fusion in the fission yeast Schizosaccharomyces pombe.
    J Gen Microbiol. 1980 Feb;116(2):525-8 PMID: 7373283
  18. Role of a ras homolog in the life cycle of Schizosaccharomyces pombe.
    Cell. 1986 Jan 31;44(2):329-36 PMID: 3002633
  19. A gene which encodes a predicted protein kinase can restore some functions of the ras gene in fission yeast.
    EMBO J. 1988 Apr;7(4):985-93 PMID: 3042386
  20. The role of sterility genes (ste and aff) in the initiation of sexual development in Schizosaccharomyces pombe.
    Mol Gen Genet. 1988 Aug;213(2-3):529-34 PMID: 3185514
  21. Genetic Mapping in SCHIZOSACCHAROMYCES POMBE by Mitotic and Meiotic Analysis and Induced Haploidization.
    Genetics. 1977 Nov;87(3):471-89 PMID: 17248775
  22. S. pombe pac1+, whose overexpression inhibits sexual development, encodes a ribonuclease III-like RNase.
    EMBO J. 1991 Jan;10(1):221-6 PMID: 1989884
  23. Mating-Type Mutations in SCHIZOSACCHAROMYCES POMBE: Isolation of Mutants and Analysis of Strains with an h or h Phenotype.
    Genetics. 1976 Jun;83(2):259-73 PMID: 17248713
  24. Mating pheromone-like diffusible factor released by Schizosaccharomyces pombe.
    EMBO J. 1986 Aug;5(8):1991-3 PMID: 16453698
Article Info
Journal
Current genetics
Abbr.
Curr Genet
ISSN
0172-8083
Published
1991-07-00
Pages
79-85
Language
English
Region
United States
NLM ID
8004904
Subset
IM
Analysis Services
Analysis Services

Contact

No. 2 Wenbo Road, Zhangqiu District, Jinan, Shandong

Qilu Normal University · Genelibs Bioinformatics Lab

750 Shunhua Rd, Jinan

2F, Bldg F, University Science Park

Tel: 0531-88819269

WeChat Official Account

Follow our WeChat subscription account for real-time updates and the latest in medical and biological research.


Business Email

E-mail: product@genelibs.com