Crosstalk between the SUMO and ubiquitin pathways.

Ernst Schering Foundation symposium proceedings ·No. 1 ·2008-00-00 ·Pages 1-16

Hunter T, Sun H

Abstract

Several ways in which the SUMO and ubiquitin pathways can intersect and communicate have recently been discovered. This review discusses the principles of crosstalk between SUMOylation and ubiquitination, focusing on the RNF4 family of RING finger E3 ubiquitin ligases, which specifically recognize SUMOylated proteins via their SUMO moiety for ubiquitination.

MeSH Terms

Animals Protein Binding RING Finger Domains Signal Transduction Small Ubiquitin-Related Modifier Proteins/metabolism Ubiquitin/metabolism Ubiquitin-Protein Ligases/chemistry,classification,metabolism

Chemicals

Small Ubiquitin-Related Modifier Proteins Ubiquitin Ubiquitin-Protein Ligases

Authors & Affiliations

2 authors, click to expand affiliations / ORCID

Hunter T

Molecular and Cell Biology Laboratory, The Salk Institute, 10010 North Torrey Pines Road, La Jolla, CA 920137-1099, USA. hunter@salk.edu

Sun H

Article Info

Journal

Ernst Schering Foundation symposium proceedings

Abbr.

Ernst Schering Found Symp Proc

DOI

10.1007/2789_2008_098

hunter@salk.edu

Published

2008-00-00

Pages

1-16

Language

English

Region

Germany

NLM ID

101312605

Subset

External Links

PubMed source DOI: 10.1007/2789_2008_098

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