Stimulation of glucagon and inhibition of insulin secretion evoked from carotid baroreceptors.

Experientia ·Vol. 33 ·No. 2 ·1977-02-15 ·Pages 236-7

Järhult J, Holst JJ

Abstract

The influence from carotid baroreceptors on portal immuno-reactive glucagon and insulin levels and on arterial plasma glucose concentration was studied in vagotomized cats by sectioning of the sinus nerves. Such a complete elimination of the afferent baroreceptor discharge caused a prompt and pronounced increase in the glucose and glucagon levels, whereas the insulin concentration significantly decreased. The role of vascular barorecptors in the hyperglycemic response to hemorrhage is discussed.

MeSH Terms

Animals Carotid Body/physiology Cats Glucagon/blood Insulin/blood Kinetics Receptors, Cell Surface/physiology Vagotomy

Chemicals

Insulin Receptors, Cell Surface Glucagon

Authors & Affiliations

2 authors, click to expand affiliations / ORCID

Järhult J

Holst J J

References (17)

17 references, click to expand

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Article Info

Journal

Experientia

Abbr.

Experientia

ISSN

0014-4754

DOI

10.1007/BF02124086

Published

1977-02-15

Pages

236-7

Language

English

Region

Switzerland

NLM ID

0376547

Subset

External Links

PubMed source DOI: 10.1007/BF02124086

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Stimulation of glucagon and inhibition of insulin secretion evoked from carotid baroreceptors.

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