Hematopoietic stem cell quiescence: yet another role for p53.
作者:
van Os(Ronald),de Haan(Gerald),Dykstra(Brad J)
状态:
发布时间2009-01-08
, 更新时间 2016-05-18
期刊:
Cell Stem Cell
摘要:
p53, sometimes referred to as the "guardian of the genome," helps regulate cell-cycle arrest, DNA-damage repair, apoptosis, and senescence. Adding to this list, in this issue of Cell Stem Cell, Liu et al. (2009) show that p53 also plays a role in regulating hematopoietic stem cell quiescence.