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PMID: 19081820 Published · ppublish English Journal Article

Rational Design of a Fluorescent Hydrogen Peroxide Probe Based on the Umbelliferone Fluorophore.

Tetrahedron letters ·Vol. 49 ·No. 19 ·2008-05-05 ·Pages 3045-3048

Du L, Li M, Zheng S, Wang B

Abstract

In this study, we report a novel water-soluble umbelliferone-based fluorescent probe for hydrogen peroxide. This probe shows very large increases (up to 100 fold) in fluorescent intensity upon reaction with hydrogen peroxide, and good selectivity over other reactive oxygen species (ROS).

Authors & Affiliations
4 authors, click to expand affiliations / ORCID
Du Lupei
Department of Chemistry and Center for Biotechnology and Drug Design, Georgia State University, Atlanta, GA 30302-4098, USA.
Li Minyong
Zheng Shilong
Wang Binghe
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Article Info
Journal
Tetrahedron letters
Abbr.
Tetrahedron Lett
ISSN
0040-4039
DOI
10.1016/j.tetlet.2008.03.063
Published
2008-05-05
Pages
3045-3048
Language
English
Region
England
NLM ID
2984819R
PMCID
PMC2490821
Grants
NCI NIH HHS · R21 CA113917-02 · United States
NCI NIH HHS · R21 CA113917 · United States
NCI NIH HHS · R21 CA113917-01 · United States
NCI NIH HHS · R21 CA123329 · United States
NCI NIH HHS · R21 CA123329-01 · United States
NCI NIH HHS · R21 CA113917-01S1 · United States
NCI NIH HHS · R21 CA123329-02 · United States
External Links
PubMed source DOI: 10.1016/j.tetlet.2008.03.063 PMC Full Text View journal details
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