Tremor caused by sympathomimetics is mediated by beta2-adrenoreceptors.

Scandinavian journal of respiratory diseases ·Vol. 58 ·No. 1 ·1977-00-00 ·Pages 5-10

Larsson S, Svedmyr N

Abstract

Tremor caused by beta-adrenostimulating drugs is known to be mediated by beta-receptors in skeletal muscles. In this study it was shown that tremor caused by terbutaline could be blocked by propranolol, a drug with both beta1- and beta2-blocking properties, but not by metoprolol, a beta1-selective antagonist. It is concluded that tremor caused by sympathomimetics in man is mainly mediated by beta2-receptors.

MeSH Terms

Blood Pressure/drug effects Heart Rate/drug effects Humans Informed Consent Metoprolol/pharmacology Propranolol/pharmacology Receptors, Adrenergic/physiology Receptors, Adrenergic, beta/physiology Sympathomimetics/pharmacology Terbutaline/antagonists & inhibitors,pharmacology Tremor/chemically induced

Chemicals

Receptors, Adrenergic Receptors, Adrenergic, beta Sympathomimetics Propranolol Metoprolol Terbutaline

Authors & Affiliations

2 authors, click to expand affiliations / ORCID

Larsson S

Svedmyr N

Article Info

Journal

Scandinavian journal of respiratory diseases

Abbr.

Scand J Respir Dis

ISSN

0036-5572

Published

1977-00-00

Pages

5-10

Language

English

Region

Denmark

NLM ID

0055427

Subset

External Links

PubMed source

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Tremor caused by sympathomimetics is mediated by beta2-adrenoreceptors.

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