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PMID: 19041421 Published · ppublish English Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't Review

The life of lipid droplets.

Biochimica et biophysica acta ·Vol. 1791 ·No. 6 ·2009-06-00 ·Pages 459-66

Walther TC, Farese RV

Abstract

Lipid droplets are the least characterized of cellular organelles. Long considered simple lipid storage depots, these dynamic and remarkable organelles have recently been implicated in many biological processes, and we are only now beginning to gain insights into their fascinating lives in cells. Here we examine what we know of the life of lipid droplets. We review emerging data concerning their cellular biology and present our thoughts on some of the most salient questions for investigation.

MeSH Terms
Acyltransferases/metabolism Animals Humans Lipid Metabolism Membrane Fusion Organelle Size Organelles/enzymology,metabolism,ultrastructure Protein Transport
Chemicals
Acyltransferases
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Walther Tobias C
Organelle Architecture and Dynamics, Max Planck Institute of Biochemistry, Martinsried, Germany. twalther@biochem.mpg.de
Farese Robert V
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Article Info
Journal
Biochimica et biophysica acta
Abbr.
Biochim Biophys Acta
ISSN
0006-3002
DOI
10.1016/j.bbalip.2008.10.009
Email
twalther@biochem.mpg.de
Published
2009-06-00
Epub
2008-00-07
Pages
459-66
Language
English
Region
Netherlands
NLM ID
0217513
PMCID
PMC2782899
Subset
IM
Grants
NIDDK NIH HHS · R21 DK078254 · United States
NIDDK NIH HHS · R21 DK078254-01 · United States
NIDDK NIH HHS · R21 DK078254-02 · United States
NIDDK NIH HHS · R21-DK78254 · United States
External Links
PubMed source DOI: 10.1016/j.bbalip.2008.10.009 PMC Full Text
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