Extreme makeover: converting one cell into another.
作者:
Zhou(Qiao),Melton(Douglas A)
状态:
发布时间2008-10-22
, 更新时间 2016-05-18
期刊:
Cell Stem Cell
摘要:
Cells of adult mammals can be converted (reprogrammed) to new cells. In one approach, adult cells are converted to pluripotent stem cells, followed by differentiation to regenerate new cell types. Alternatively, adult cells may be directly converted into other mature cells or progenitors. We discuss and compare these two approaches with particular emphasis on the latter and its relevance for regenerative medicine.