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PMID: 18804170 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't

A survey of nonribosomal peptide synthetase (NRPS) genes in Aspergillus nidulans.

Fungal genetics and biology : FG & B ·Vol. 46 Suppl 1 ·2009-03-00 ·Pages S45-52

von Döhren H

Abstract

The genome of Aspergillus nidulans carries 27 genes encoding nonribosomal peptide synthetase (NRPS) structures, although only five of these forming peptides and amino acid containing metabolites have been identified so far. This manuscript describes domain structures, substrate binding pockets and related genes and gene clusters and summarizes our current state of product prediction of fungal NRPS systems.

MeSH Terms

Aspergillus nidulans/genetics Binding Sites Fungal Proteins/genetics Metabolic Networks and Pathways/genetics Multigene Family Peptide Synthases/genetics Protein Structure, Tertiary

Chemicals

Fungal Proteins Peptide Synthases non-ribosomal peptide synthase

Authors & Affiliations

1 authors, click to expand affiliations / ORCID

von Döhren Hans

Technical University Berlin, Institute of Chemistry OE2, Franklinstr. 29, 10587 Berlin, Germany. doehren@chem.tu-berlin.de

Article Info

Journal

Fungal genetics and biology : FG & B

Abbr.

Fungal Genet Biol

ISSN

1096-0937

DOI

10.1016/j.fgb.2008.08.008

doehren@chem.tu-berlin.de

Published

2009-03-00

Epub

2008-00-03

Pages

S45-52

Language

English

Region

United States

NLM ID

9607601

Subset

External Links

PubMed source DOI: 10.1016/j.fgb.2008.08.008 View journal details

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A survey of nonribosomal peptide synthetase (NRPS) genes in Aspergillus nidulans.

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