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PMID: 187775 Published · ppublish English Journal Article Research Support, U.S. Gov't, P.H.S.

In vitro susceptibility of mink lung cells to the mouse mammary tumor virus.

Journal of the National Cancer Institute ·Vol. 57 ·No. 2 ·1976-08-00 ·Pages 447-9

Lasfargues EY, Vaidya AB, Lasfargues JC, Moore DH

Abstract

Lung cells from mink embryos were infected in vitro with a purified mammary tumor virus isolated from RIII mouse milk. Specific virus antigen at the cell surface was detected by membrane immunofluorescence; B-type virions budding from the cell membrane were seen by electron microscopy. Nucleic acid hybridization confirmed replication and specificity of the virus produced.

MeSH Terms

Animals Antigens, Neoplasm Antigens, Viral Cell Membrane/immunology,ultrastructure Cell Transformation, Neoplastic Cells, Cultured Female Lung/microbiology Mammary Tumor Virus, Mouse/growth & development Mice Mink Pregnancy Virus Replication

Chemicals

Antigens, Neoplasm Antigens, Viral

Authors & Affiliations

4 authors, click to expand affiliations / ORCID

Lasfargues E Y

Vaidya A B

Lasfargues J C

Moore D H

Article Info

Journal

Journal of the National Cancer Institute

Abbr.

J Natl Cancer Inst

ISSN

0027-8874

DOI

10.1093/jnci/57.2.447

Published

1976-08-00

Pages

447-9

Language

English

Region

United States

NLM ID

7503089

Subset

External Links

PubMed source DOI: 10.1093/jnci/57.2.447 View journal details

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In vitro susceptibility of mink lung cells to the mouse mammary tumor virus.

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