[TRP channels and mechanical stress].

Clinical calcium ·Vol. 18 ·No. 9 ·2008-09-00 ·Pages 1304-11

Mizuno A

Abstract

Transient receptor potential (TRP) channels respond to diverse external stimuli and convert them into intracellular calcium signals. Recent evidence shows that TRPV4, one of the vanilloid subfamily, plays a key role in mechanosensation in bone. Here I summarize the current knowledge on possible functions of TRP channels.

MeSH Terms

Animals Bone Density Bone and Bones/cytology,metabolism Calcium Signaling/genetics,physiology Humans Mechanotransduction, Cellular/genetics,physiology Mice Osteogenesis/genetics,physiology Stress, Mechanical TRPC Cation Channels/physiology

Chemicals

TRPC Cation Channels TRPC4 ion channel

Authors & Affiliations

1 authors, click to expand affiliations / ORCID

Mizuno Atsuko

Jichi Medical University.

Article Info

Journal

Clinical calcium

Abbr.

Clin Calcium

ISSN

0917-5857

DOI

CliCa080913041311

Published

2008-09-00

Pages

1304-11

Language

jpn

Region

Japan

NLM ID

9433326

Subset

External Links

PubMed source DOI: CliCa080913041311

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[TRP channels and mechanical stress].

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